A Xbox 360 tem vasta biblioteca multijogador: local, System Link ou Xbox Live (requer subscrição paga).
Shooters
FPS: Halo 3, Call of Duty Black Ops, Battlefield: Bad Company 2.
Third-person: Gears of War 2, Tom Clancy's Splinter Cell Conviction, 50 Cent: Blood on the Sand.
Luta
Super Street Fighter IV, Mortal Kombat, Marvel vs. Capcom 3, WWE All-Stars. Clássicos como Super Street Fighter II Turbo e Marvel vs. Capcom 2 no Xbox Live Arcade.
Corridas
Simulação: Forza Motorsport 3, Shift 2: Unleashed, Dirt 3.
Arcade: Burnout: Paradise, Split/Second, Need for Speed: Hot Pursuit.
Ação/Aventura
Red Dead Redemption, Dead Rising 2, Red Faction: Guerilla (ação). Fable III, série LEGO, Marvel Ultimate Alliance (aventura/RPG).
Desporto
Equipas: Madden, NBA 2K11, FIFA. Individuais: EA Sports MMA, Fight Night: Champion, Tiger Woods PGA Tour.
Outros
Música: Rock Band 3, Guitar Hero. Trivia: You Don't Know Jack, Scene It? Mistos: Banjo-Kazooie: Nuts and Bolts, Portal 2.
